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Larry Zeitlin;Ognian Bohorov;Natasha Bohorova;Andrew Hiatt;Do Kim;Michael Pauly;Jesus Velasco;Kevin Whaley;Dale Barnard;John Bates;James Crowe;Pedro Piedra;Brian Gilbert;

2013

2013, vol.5, no.2

Engineering a therapeutic IgG molecule to address cysteinylation, aggregation and enhance thermal stability and expression

Andrew Buchanan;Veronica Clementel;Rob Woods;Nicholas Harn;Michael A Bowen;Wenjun Mo;Bojana Popovic;Steven M. Bishop;William Dall’Acqua;Ralph Minter;Lutz Jermutus;Vahe Bedian;

2013

2013, vol.5, no.2

Rapid optimization and prototyping for therapeutic antibody-like molecules

Lihui Xu;Neeraj Kohli;Rachel Rennard;Yang Jiao;Maja Razlog;Kathy Zhang;Jason Baum;Bryan Johnson;Jian Tang;Birgit Schoeberl;Jonathan Fitzgerald;Ulrik Nielsen;Alexey A. Lugovskoy;

2013

2013, vol.5, no.2

Novel asymmetrically engineered antibody Fc variant with superior FcγR binding affinity and specificity compared with afucosylated Fc variant

Futa Mimoto;Tomoyuki Igawa;Taichi Kuramochi;Hitoshi Katada;Shojiro Kadono;Takayuki Kamikawa;Meiri Shida-Kawazoe;Kunihiro Hattori;

2013

2013, vol.5, no.2

Mutation of Y407 in the CH3 domain dramatically alters glycosylation and structure of human IgG

Rebecca J. Rose;Patrick H.C. van Berkel;Ewald T.J. van den Bremer;Aran F. Labrijn;Tom Vink;Janine Schuurman;Albert J.R. Heck;Paul W.H.I. Parren;

2013

2013, vol.5, no.2

Monoclonal antibody therapeutics with up to five specificities: Functional enhancement through fusion of target-specific peptides

David LaFleur;Donara Abramyan;Palanisamy Kanakaraj;Rodger Smith;Rutul Shah;Geping Wang;Xiao-Tao Yao;Spandana Kankanala;Ernest Boyd;Liubov Zaritskaya;Viktoriya Nam;Bridget Puffer;Pete Buasen;Shashi Kaithamana;Andrew Burnette;Rajesh Krishnamurthy;Dimki Patel;Viktor Roschke;Peter Kiener;David Hilbert;Carlos Barbas;

2013

2013, vol.5, no.2

Treatment of children with high grade glioma with nimotuzumab: A 5-y institutional experience

Ricardo Cabanas;Giselle Saurez;Martha Rios;José Alert;Adnolys Reyes;Jose Valdes;Maria C. Gonzalez;Jorge L. Pedrayes;Melba Avila;Raiza Herrera;Mariela Infante;Ernesto Echevarria;Myrna Moreno;Patricia Lorenzo Luaces;Tania Crombet Ramos;

2013

2013, vol.5, no.2